WHO 在 2021/5/26 開會討論免疫橋接 (Immunobridging) :
WHO Meeting on correlates of protection: COVID-19 vaccines
1 June 2021 13:00 – 18:40 UTC Time
A deeper understanding of correlates of protection would greatly help new vaccine and modified vaccines development (and extension of existing vaccinesto new populations).
OBJECTIVES OF THE MEETING
1. To outline the role of immunobridging in the evaluation of COVID-19 vaccines (current vaccines, modified vaccines, new vaccines)
2. To enumerate the data that would be required to inform decisions on immunobridging and correlates of protection.
3. To discuss what is the role of the various assays and animal models and what are the current limitations with interpretation of results.
4. To debate on the design and analysis of clinical studies to define correlates of protection (non-inferiority vs superiority, selection of comparator and end points)
5. To review the current data and define a research agenda.
該網頁可觀看會議視頻
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另外,The Global Health Network 提供了一個 Workshop 的簡報下載:
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這個議題目前還在討論中,尚未有定論!
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中和抗體 (neutralizing antibody) 的免疫保護力研究